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Anti-COX4 antibody[STJ97368]

Product nameAnti-COX4 antibodyShort DescriptionRabbit polyclonal against COX4DescriptionRabbit polyclonal to COX4.

市场价￥600
 
 


  • Product nameAnti-COX4
    Product nameAnti-COX4 antibody
    Short DescriptionRabbit polyclonal against COX4
    DescriptionRabbit polyclonal to COX4.
    ApplicationsIHC-p, WB
    Dilution rangeWB 1:1000
    IHC 1:500-1000
    SpecificityThe antibody detects endogenous COX4 protein.
    Protein NameCytochrome C Oxidase Subunit 4 Isoform 1-Mitochondrial
    Cytochrome C Oxidase Polypeptide Iv
    Cytochrome C Oxidase Subunit Iv Isoform 1
    Cox Iv-1
    ImmunogenRecombinant Protein
    Storage InstructionStore at-20°C, and avoid repeat freeze-thaw cycles.
    NoteFOR RESEARCH USE ONLY (RUO).
    HostRabbit
    ClonalityPolyclonal
    ReactivityHuman, Mouse, Rat
    ConjugationUnconjugated
    PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    IsotypeIgG
    FormulationPBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
    Gene ID1327
    Gene SymbolCOX4I1
    Database LinksHGNC:2265
    OMIM:123864
    Alternative NamesAnti-Cytochrome C Oxidase Subunit 4 Isoform 1-Mitochondrial antibody
    Anti-Cytochrome C Oxidase Polypeptide Iv antibody
    Anti-Cytochrome C Oxidase Subunit Iv Isoform 1 antibody
    Anti-Cox Iv-1 antibody
    Anti-COX4I1 COX4 antibody
    FunctionComponent of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunbit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
    Cellular LocalizationMitochondrion Inner Membrane
    Single-Pass Membrane Protein
     


  • Anti-COX4 antibody[STJ97368](图1)



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