Anti-IL-17 alpha antibody[STJ93683]
Product nameAnti-IL-17 alpha antibodyShort DescriptionRabbit polyclonal against IL-17 alphaDescriptionRabbit polyclonal to IL
![Anti-IL-17 alpha antibody[STJ93683]](/uploads/allimg/20200408/1-20040Q25PI24.jpg)
Product nameAnti-IL-17 alpha antibodyShort DescriptionRabbit polyclonal against IL-17 alphaDescriptionRabbit polyclonal to IL
| Product name | Anti-IL-17 alpha antibody[STJ93683] |
|---|---|
| Short Description | Rabbit polyclonal against IL-17 alpha |
| Description | Rabbit polyclonal to IL-17Ralpha. |
| Applications | ELISA, WB |
| Dilution range | WB 1:500-1:2000 ELISA 1:40000 |
| Specificity | IL-17Ralpha Polyclonal Antibody detects endogenous levels of IL-17Ralpha protein. |
| Protein Name | Interleukin-17 receptor A IL-17 receptor A IL-17RA CDw217 CD antigen CD217 |
| Immunogen | Synthesized peptide derived from human IL-17Ralpha |
| Immunogen Region | 110-190 aa, Internal |
| Storage Instruction | Store at -20°C, and avoid repeat freeze-thaw cycles. |
| Note | For Research Use Only (RUO). |
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Conjugation | Unconjugated |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Isotype | IgG |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene ID | 23765 |
|---|---|
| Gene Symbol | IL17RA |
| Molecular Weight | 90 kDa |
| Database Links | HGNC:5985 OMIM:605461 |
| Alternative Names | Interleukin-17 receptor A IL-17 receptor A IL-17RA CDw217 CD antigen CD217 |
| Function | Receptor for IL17A . Receptor for IL17F . Binds to IL17A with higher affinity than to IL17F . Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC . Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC . Receptor for IL17C as part of a heterodimeric complex with IL17RE . Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6 . |
| Post-translational Modifications | Glycosylated. |
| Cellular Localization | Isoform 1: Cell membrane Isoform 2: Secreted |
| Tissue Specificity | Widely expressed. |
| Swiss-Prot Key | Q96F46_HUMAN |
](/uploads/ueditor/20200917/1-20091G62533R5.png "Anti-IL-17 alpha antibody[STJ93683](图1)")
