Anti-IL-17RC antibody[STJ93682]
Product nameAnti-IL-17RC antibodyShort DescriptionRabbit polyclonal against IL-17RCDescriptionRabbit polyclonal to IL-17RC.Ap
Product nameAnti-IL-17RC antibodyShort DescriptionRabbit polyclonal against IL-17RCDescriptionRabbit polyclonal to IL-17RC.Ap
| Product name | Anti-IL-17RC antibody[STJ93682] |
|---|---|
| Short Description | Rabbit polyclonal against IL-17RC |
| Description | Rabbit polyclonal to IL-17RC. |
| Applications | ELISA, WB |
| Dilution range | WB 1:500-1:2000 ELISA 1:20000 |
| Specificity | IL-17RC Polyclonal Antibody detects endogenous levels of IL-17RC protein. |
| Protein Name | Interleukin-17 receptor C IL-17 receptor C IL-17RC Interleukin-17 receptor homolog IL17Rhom Interleukin-17 receptor-like protein IL-17RL ZcytoR14 |
| Immunogen | Synthesized peptide derived from human IL-17RC |
| Immunogen Region | 680-760 aa, C-terminal |
| Storage Instruction | Store at -20°C, and avoid repeat freeze-thaw cycles. |
| Note | For Research Use Only (RUO). |
| Validated Application | ](/uploads/ueditor/20200408/1-20040Q2463X19.png "Anti-IL-17RC antibody[STJ93682](图1)"){kind=small} |
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Reactivity | Human |
| Conjugation | Unconjugated |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Isotype | IgG |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene ID | 84818 |
|---|---|
| Gene Symbol | IL17RC |
| Molecular Weight | 70 kDa |
| Database Links | HGNC:18358 OMIM:610925 |
| Alternative Names | Interleukin-17 receptor C IL-17 receptor C IL-17RC Interleukin-17 receptor homolog IL17Rhom Interleukin-17 receptor-like protein IL-17RL ZcytoR14 |
| Function | Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA . Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA . Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA . Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1 . Isoform 5: Receptor for both IL17A and IL17F. Isoform 6: Does not bind IL17A or IL17F. Isoform 7: Does not bind IL17A or IL17F. Isoform 8: Receptor for both IL17A and IL17F. |
| Cellular Localization | Cell membrane. Soluble isoforms may be produced. |
| Tissue Specificity | Expressed in prostate, skeletal muscle, kidney and placenta (at protein level) . Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate . Also detected in thyroid, trachea and adrenal gland . Low expression in thymus and leukocytes . |
| Swiss-Prot Key | Q8NAC3_HUMAN |
](/uploads/ueditor/20200917/1-20091GG00H26.png "Anti-IL-17RC antibody[STJ93682](图2)")
