Anti-GFAP antibody[STJ180110]
Product nameAnti-GFAP antibodyShort DescriptionPurified Anti-GFAP antibody [STJ180110] which is suitable for use in IHC. Avai
Product name | Anti-GFAP antibody[STJ180110] |
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Short Description | Purified Anti-GFAP antibody [STJ180110] which is suitable for use in IHC. Available as concentrated or predilute options |
Description | Glial Fibrillary Acidic Protein (GFAP) is specific to astrocytes (i.e., glial cells) and ependymal cells of the central nervous system. MAb to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS. GFAP stains astrocytes, glial cells, ependymal cells, and their corresponding tumors. Many types of neural tumors such as neuroblastomas, Schwannomas, as well as extra‐CNS tumors are not labeled. GA‐5 is very sensitive in detecting GFAP in routine formalin‐fixed, paraffin‐embedded tissues. |
Applications | IHC-p |
Dilution range | 1:100‐200 |
Protein Name | Glial Fibrillary Acidic Protein Gfap |
Immunogen | Native GFAP purified from pig spinal cord |
Storage Instruction | Store at 2-8°C for up to 1 year |
Note | For Research Use Only (RUO). |
Host | Mouse |
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Clonality | Monoclonal |
Clone ID | GA‐5 |
Reactivity | Human |
Conjugation | Unconjugated |
Isotype | IgG1κ |
Formulation | Purified antibody diluted in Tris‐HCI buffer containing stabilizing protein and <0.1% sodium azide. |
Gene ID | 2670 |
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Gene Symbol | |
Molecular Weight | 50 kDa |
Alternative Names | Anti-Glial Fibrillary Acidic Protein antibody Anti-Gfap antibody Anti-GFAP antibody |
Function | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
Post-translational Modifications | Phosphorylated by PKN1. |
Cellular Localization | Cytoplasm Associated With Intermediate Filaments |
Tissue Specificity | Expressed in cells lacking fibronectin. |
Swiss-Prot Key | GFAP_HUMAN |