Anti-GRP78 BiP antibody[STJ98969]
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
| Product name | Anti-GRP78 BiP antibody[STJ98969] |
|---|---|
| Short Description | Rabbit polyclonal against GRP78 BiP |
| Description | Rabbit polyclonal to GRP78 BiP. |
| Applications | ELISA, IHC-p, WB |
| Dilution range | WB 1:500-2000 IHC-p 1:500-200 ELISA 1:10000-20000 |
| Specificity | The antibody detects endogenous GRP78 BiP |
| Protein Name | 78 kDa glucose-regulated protein GRP-78 Endoplasmic reticulum lumenal Ca 2+-binding protein grp78 Heat shock 70 kDa protein 5 Immunoglobulin heavy chain-binding protein BiP |
| Immunogen | Synthetic peptide from human GRP78 BiP protein. |
| Immunogen Region | 505-570 aa |
| Storage Instruction | Store at-20°C, and avoid repeat freeze-thaw cycles. |
| Note | FOR RESEARCH USE ONLY (RUO). |
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Isotype | IgG |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene ID | 3309 |
|---|---|
| Gene Symbol | HSPA5 |
| Molecular Weight | 78kDa |
| Database Links | HGNC:5238 OMIM:138120 |
| Alternative Names | 78 kDa glucose-regulated protein GRP-78 Endoplasmic reticulum lumenal Ca 2+-binding protein grp78 Heat shock 70 kDa protein 5 Immunoglobulin heavy chain-binding protein BiP |
| Function | Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate. |
| Cellular Localization | Endoplasmic reticulum lumen Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Swiss-Prot Key | P11021_HUMAN |
](/uploads/ueditor/20200909/1-200Z910561aW.png "Anti-GRP78 BiP antibody[STJ98969](图1)")
